Current evidence supporting "letrozole" for ovulation induction

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P-62: Extended Letrozole Therapy for Ovulation Induction in Women with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in young women which has different clinical consequences. This study was conducted to evaluate the outcome of long or extended letrozole therapy for induction of ovulation in patients with polycystic ovary syndrome (PCOS). Materials and Methods: This prospective controlled study was conducted in a university hospital on...

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The Use of High Dose Letrozole in Ovulation Induction and Controlled Ovarian Hyperstimulation

Letrozole, an aromatase inhibitor, has been demonstrated to be effective as an ovulation induction and controlled ovarian hyperstimulation agent. However, dose administration has generally been limited to 5 days at 2.5 to 7.5 mg daily. We undertook a retrospective review of over 900 treatment cycles using letrozole in doses as high as 12.5 mg per day. Results indicate that such doses do indeed ...

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Ovulation induction in polycystic ovary syndrome: Current options.

There are a variety of effective treatment options to induce ovulation in women with polycystic ovary syndrome (PCOS). The most effective treatments are primarily reproductive and target the hypothalamic-pituitary-ovarian (HPO) axis. Letrozole, an aromatase inhibitor, is headed toward replacing clomiphene, a selective estrogen receptor modulator, as the first-choice option. Metabolic treatments...

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Comparison of the effects of letrozole and clomiphene citrate for ovulation induction in infertile women with polycystic ovary syndrome.

AIM Ovulation dysfunction is one of the most common causes of reproductive failure in infertile couples. The prevalence of this disorder in infertile women is about 30 to 40%. Polycystic ovary syndrome is a common disease that is closely related to ovulation dysfunction and 7% of women of childbearing age are afflicted with it. Ovulation induction is a way to treat infertility in PCOS which is ...

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Aromatase Inhibitor for Ovulation Induction: a Comparative Study between Letrozole and Clomiphen Citrate in Anovulatory Infertile Women

The study was designed to compare the effectiveness of Letrozole and clomiphen citrate in the treatment of anovulatorv infertility. Thirty patients were selected randomly who had anovulatorv infertility. In letrozole group, fifteen patients got 5-7.5 mg of letrozole orally and in clomiphen citrate group, 100-150 mg of clomiphen citrate was given orally for maximum of six cycles and in both the ...

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ژورنال

عنوان ژورنال: Journal of Human Reproductive Sciences

سال: 2013

ISSN: 0974-1208

DOI: 10.4103/0974-1208.117166